In this paper, the problem of aperiodic intermittent control for nonlinear stochastic time-delay systems based on discrete-time observations is studied. Combining the discrete feedback control strategy with the intermittent control strategy, an aperiodic intermittent feedback controller for observing the state of the system in discrete time is designed, which makes the controlled system reach mean square exponential stability. The conditions for system stability are established through M-matrix theory and intermittent control strategy, and the mean square exponential stability of nonlinear stochastic time-delay systems is proved by Lyapunov function and It\^{o} formula. Finally, a numerical example was provided to demonstrate the correctness of the theoretical derivation.