The problem of fuzzy adaptive event-triggered fault-tolerant control is developed for uncertain nonlinear systems with unknown control directions, unknown nonlinear functions and actuator faults. Firstly, the adaptive event-triggered fault-tolerant controller and the adaptive laws are constructed by combining the backstepping method and theoretical knowledge about fuzzy logic system, which can effectively compensate the influence of actuator faults on the system. Secondly, the Nussbaum function is introduced into the design of the adaptive event-triggered fault-tolerant controller. Finally, the control scheme is designed to ensure that the closed-loop signal is uniformly and ultimately bounded within a given compact set, and the effectiveness of the proposed control scheme is verified through simulation results.