Association Journal of CSIAM
Supervised by Ministry of Education of PRC
Sponsored by Xi'an Jiaotong University
ISSN 1005-3085  CN 61-1269/O1

Chinese Journal of Engineering Mathematics ›› 2023, Vol. 40 ›› Issue (3): 413-424.doi: 10.3969/j.issn.1005-3085.2023.03.006

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Global Stability of an Epidemic Model with Age-structure

WANG Fei,  FU Liting   

  1. College of Mathematics and Physics, Xinjiang Agricultural University, Urumqi 830052
  • Received:2021-02-18 Accepted:2022-12-15 Online:2023-06-15 Published:2023-08-15
  • Supported by:
    The College Scientific Research Project of Xinjiang Uygur Autonomous Region (XJEDU2018Y021); the College Student Innovation and Entrepreneurship Training Program (dxscx2023492).

Abstract:

Based on reinfection, an epidemic model with vaccination, incubation and infection ages is presented to understand the impact of age of vaccination, age of latency and age of infection on global dynamics of the model. It is shown that the global dynamics of the model is determined by the basic regeneration number. First, the boundedness, existence, nonnegativity and asymptotic smoothness of the model are established by the theory of integrating partial differential equations along characteristic lines. Then, the steady states and basic reproduction number of the model are obtained by the theory of solutions to differential equations. By constructing a suitable Lyapunov functional and using the LaSalle invariance principle, it is verified that the disease-free steady state is globally asymptotically stable if the basic regeneration number is less than 1, and unstable if the basic regeneration number is larger than 1. Finally, by numerical simulation it is verified that the solution converges to the disease-free equilibrium point.

Key words: age-structured, infection age, reinfection, stability, asymptotic smoothness

CLC Number: