Association Journal of CSIAM
Supervised by Ministry of Education of PRC
Sponsored by Xi'an Jiaotong University
ISSN 1005-3085  CN 61-1269/O1

Chinese Journal of Engineering Mathematics ›› 2022, Vol. 39 ›› Issue (5): 750-762.doi: 10.3969/j.issn.1005-3085.2022.05.006

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Dynamic Behavior of an HIV Infection Model with Intracellular Delay

XING Qinghong,   LI Can,   MA Huilian,   GUO Zunguang   

  1. Department of Science, Taiyuan Institute of Technology, Taiyuan 030008
  • Online:2022-10-15 Published:2022-12-15
  • Contact: Z. Guo. E-mail address: guozg@tit.edu.cn
  • Supported by:
    The Natural Science Foundation of Shanxi Province (201901D111322); the Program for the (Reserved) Discipline Leaders of Taiyuan Institute of Technology (201808); the Scientific Research Foundation of Taiyuan Institute of Technology (2022KJ070).

Abstract:

An HIV infection dynamics model with intracellular delay is studied. The basic reproduction ratio is obtained by calculation. By analyzing the distribution of roots of the corresponding characteristic equations, the local stability of each of feasible equilibria is established. By constructing the suitable Lyapunov functional, it is proved that if the basic reproduction ratio is less than unity, the infection-free equilibrium is globally asymptotically stable. From the persistence theory of infinite dimensional dynamic system, it shows that if the basic reproduction ratio is greater than unity, the system is uniformly persistent. According to the iteration technique and comparision arguments, the sufficient conditions are obtained for the global attractivity of the chronic infection equilibrium.

Key words: intracellular time delay, saturation incidence, the basic reproduction ratio, stability

CLC Number: